2020 Summit Speaker Series

2020 Summit Speaker Series

Previous Sessions

Session One:

Building a Trans-Canada Railway for CAR T-Cell Therapies
Monday, November 16, 2020, starting at 1:45pm EST / 10:45am PST

Chimeric Antigen Receptor T-cell (CAR T) therapy is a powerful tool for treating hematologic cancers and has begun to provide hope to patients without other therapeutic options to treat and cure their disease. This session, “Building a trans-Canada railway for CAR T-cell therapies,” will include talks by four speakers who are members of a collaborative effort to enable the development of Canadian capacity for point-of-care CAR T-cell manufacturing. Dr. Natasha Kekre will speak about the development of the flagship ‘made-in-Canada’ CD19 CAR T phase 1 clinical trial. Dr. Brad Nelson will discuss the development and manufacture of CAR T therapies and ensuing infrastructure and capacity development that will pave the way to enable more Canadian patients to access this new technology. Dr. Kevin Hay will present research on the development of a CD22 CAR, and Dr. Scott McComb will discuss future steps, including the development of a multi-targeted CARs, broader application of CARs to solid tumours, and other disease indications.

Learn more about CAR T in Canada

Speakers

Natasha Kekre

Dr. Natasha Kekre

Where we started: CLIC-01 CAR T clinical trial

Brad Nelson

Dr. Brad Nelson

Where we are: Point-of-care manufacturing

Kevin Hay

Dr. Kevin Hay

Where we are going next: Development of CD22 CAR T

Scott McComb

Dr. Scott McComb

What the future holds: novel CAR T design

Terry Hawrysh

Terry Hawrysh

Plain Language Summary Facilitator

Julian Smazynski

Julian Smazynski

Plain Language Facilitator

Natasha Kekre
Dr. Natasha Kekre
Where we started: CLIC-01 CAR T clinical trial
Brad Nelson
Dr. Brad Nelson
Where we are: Point-of-care manufacturing
Kevin Hay
Dr. Kevin Hay
Where we are going next: Development of CD22 CAR T
Scott McComb
Dr. Scott McComb
What the future holds: novel CAR T design

Who should attend?

Scientific and health care community including researchers, clinicians and HQP along with patients and caregivers. Note: There will be a plain language overview before the session begins and an opportunity to ask questions after the discussion.

Schedule (all times in EST)

1:45 pm - Julian Smazynski, PhD student with Dr. Brad Nelson, BCCA will provide a plain language overview of the talks. Terry Hawrysh will provide a plain language overview of the talks from a patient perspective.
2:00 pm - Talks by Drs. Natasha Kekre (OHRI), Brad Nelson (BCCA), Kevin Hay (BCCA) and Scott McComb (National Research Council of Canada)
3:00 pm - Q&A from plain language audience with Terry Hawrysh and Julian Smazynski
3:15 pm - Session end

You can read more about these research projects and biomanufacturing facilities here: